Integrative transcriptomic analysis reveals key drivers of acute peanut allergic reactions
Rising rates of peanut allergy pose a public health problem. Here, the authors profile blood transcriptomes during double-blind, placebo-controlled oral challenge in peanut-allergic children to identify gene and cell composition changes, and construct causal networks to detect key allergic reaction ...
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Bibliographic Details
Main Authors: |
C. T. Watson,
A. T. Cohain,
R. S. Griffin,
Y. Chun,
A. Grishin,
H. Hacyznska,
G. E. Hoffman,
N. D. Beckmann,
H. Shah,
P. Dawson,
A. Henning,
R. Wood,
A. W. Burks,
S. M. Jones,
D. Y. M. Leung,
S. Sicherer,
H. A. Sampson,
A. J. Sharp,
E. E. Schadt,
S. Bunyavanich |
Format: | Article
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Language: | English |
Published: |
Nature Publishing Group
2017-12-01
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Series: | Nature Communications
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Online Access: | https://doi.org/10.1038/s41467-017-02188-7
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