Dexamethasone for Severe COVID-19: How Does It Work at Cellular and Molecular Levels?

Dexamethasone for Severe COVID-19: How Does It Work at Cellular and Molecular Levels?

The coronavirus disease 2019 (COVID-19) caused by infection of the severe respiratory syndrome coronavirus-2 (SARS-CoV-2) significantly impacted human society. Recently, the synthetic pure glucocorticoid dexamethasone was identified as an effective compound for treatment of severe COVID-19. However,...

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Bibliographic Details
Main Authors: Tomoshige Kino, Irina Burd, James H. Segars
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
glucocorticoids
glucocorticoid receptor (GR)
inflammation
innate immunity
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
type I interferons (IFNs)
Online Access:https://www.mdpi.com/1422-0067/22/13/6764

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