Human Ovarian Cancer Tumor Formation in Severe Combined Immunodeficient (SCID) Pigs

Human Ovarian Cancer Tumor Formation in Severe Combined Immunodeficient (SCID) Pigs

Ovarian cancer (OvCa) is the most lethal gynecologic malignancy, with two-thirds of patients having late-stage disease (II-IV) at diagnosis. Improved diagnosis and therapies are needed, yet preclinical animal models for ovarian cancer research have primarily been restricted to rodents, for data on w...

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Bibliographic Details
Main Authors: Adeline N. Boettcher, Matti Kiupel, Malavika K. Adur, Emiliano Cocco, Alessandro D. Santin, Stefania Bellone, Sara E. Charley, Barbara Blanco-Fernandez, John I. Risinger, Jason W. Ross, Christopher K. Tuggle, Erik M. Shapiro
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Oncology
Subjects:
ovarian cancer
severe combined immunodeficient
swine
preclinical animal model
Claudin
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00009/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00009/full

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