Estrogen Receptor Alpha Gene Single Nucleotide Polymorphisms, +2464 C/T and -4576A/C, and Breast Cancer Risk, a Hospital-Based Case-Control Study

Estrogen Receptor Alpha Gene Single Nucleotide Polymorphisms, +2464 C/T and -4576A/C, and Breast Cancer Risk, a Hospital-Based Case-Control Study

Background: Estrogen is a risk factor for the development of breast cancer. The effect of estrogen is primarily mediated by estrogen receptor alpha 1 (ESR1). In this study, we investigated the association between breast cancer risk and the frequency of alleles and genotypes for two ESR1 single nucl...

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Bibliographic Details
Main Authors: Ali Akbar Amirzargar, Maryam Sadr, Samira Esmaeili Reykande, Elham Mohebbi, Mohammad Shirkhoda, Majid Mahmoodi
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2019-05-01
Series:Basic & Clinical Cancer Research
Subjects:
Estradiol receptor
Single nucleotide polymorphism
Breast neoplasm
Association study
Online Access:https://bccr.tums.ac.ir/index.php/bccrj/article/view/312

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