Hydrogen Sulfide Regulates Krüppel‐Like Factor 5 Transcription Activity via Specificity Protein 1 S‐Sulfhydration at Cys664 to Prevent Myocardial Hypertrophy

Hydrogen Sulfide Regulates Krüppel‐Like Factor 5 Transcription Activity via Specificity Protein 1 S‐Sulfhydration at Cys664 to Prevent Myocardial Hypertrophy

Background Hydrogen sulfide (H2S) is a gasotransmitter that regulates multiple cardiovascular functions. Krüppel‐like factor 5 (KLF5) exerts diverse functions in the cardiovascular system. Whether and how H2S regulates KLF5 in myocardial hypertrophy is unknown. Methods and Results In our study, hype...

Full description

Bibliographic Details
Main Authors: Guoliang Meng, Yujiao Xiao, Yan Ma, Xin Tang, Liping Xie, Jieqiong Liu, Yue Gu, Ying Yu, Chung‐Min Park, Ming Xian, Xin Wang, Albert Ferro, Rui Wang, Philip K. Moore, Zhiren Zhang, Hong Wang, Yi Han, Yong Ji
Format: Article
Language:English
Published: Wiley 2016-09-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
atrial natriuretic peptide
hydrogen sulfide
Krüppel‐like factor 5
myocardial hypertrophy
specificity protein 1
S‐sulfhydration
Online Access:https://doi.org/10.1161/JAHA.116.004160

Internet

https://doi.org/10.1161/JAHA.116.004160

Similar Items