Data integration by multi-tuning parameter elastic net regression
Abstract Background To integrate molecular features from multiple high-throughput platforms in prediction, a regression model that penalizes features from all platforms equally is commonly used. However, data from different platforms are likely to differ in effect sizes, the proportion of predictive...
Main Authors: | Jie Liu, Gangning Liang, Kimberly D Siegmund, Juan Pablo Lewinger |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-10-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-018-2401-1 |
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