Varying Presentations of Multisystem Inflammatory Syndrome Temporarily Associated with COVID-19

Background. A novel coronavirus identified in 2019 leads to a pandemic of severe acute respiratory distress syndrome with important morbidity and mortality. Initially, children seemed minimally affected, but there were reports of cases similar to (atypical) Kawasaki disease or toxic shock syndrome,...

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Main Authors: Jasmina Krikilion, Lisa Nuyttens, Siel Daelemans, Karlien François, Reiner Mauel, Daniel De Wolf, Gerlant van Berlaer
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2020/8878946
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spelling doaj-b2374764ad7643d9af08c0519e84c1132020-12-07T09:08:26ZengHindawi LimitedCase Reports in Pediatrics2090-68032090-68112020-01-01202010.1155/2020/88789468878946Varying Presentations of Multisystem Inflammatory Syndrome Temporarily Associated with COVID-19Jasmina Krikilion0Lisa Nuyttens1Siel Daelemans2Karlien François3Reiner Mauel4Daniel De Wolf5Gerlant van Berlaer6Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Department of Paediatrics, Brussel, BelgiumVrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Department of Paediatrics, Brussel, BelgiumVrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Department of Paediatrics, Brussel, BelgiumVrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Division of Nephrology and Hypertension, Brussel, BelgiumVrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Department of Paediatrics, Brussel, BelgiumVrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Department of Paediatrics, Brussel, BelgiumVrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Paediatric Emergency and Intensive Care Unit, Brussel, BelgiumBackground. A novel coronavirus identified in 2019 leads to a pandemic of severe acute respiratory distress syndrome with important morbidity and mortality. Initially, children seemed minimally affected, but there were reports of cases similar to (atypical) Kawasaki disease or toxic shock syndrome, and evidence emerges about a complication named paediatric inflammatory multisystem syndrome temporarily associated with SARS-CoV-2 (PIMS-TS) or multisystem inflammatory syndrome in children (MIS-C). Case Presentations. Two cases were compared and discussed demonstrating varying presentations, management, and evolution of MIS-C. These cases are presented to increase awareness and familiarity among paediatricians and emergency physicians with the different clinical manifestations of this syndrome. Discussion. MIS-C may occur with possible diverse clinical presentations. Early recognition and treatment are paramount for a beneficial outcome.http://dx.doi.org/10.1155/2020/8878946
collection DOAJ
language English
format Article
sources DOAJ
author Jasmina Krikilion
Lisa Nuyttens
Siel Daelemans
Karlien François
Reiner Mauel
Daniel De Wolf
Gerlant van Berlaer
spellingShingle Jasmina Krikilion
Lisa Nuyttens
Siel Daelemans
Karlien François
Reiner Mauel
Daniel De Wolf
Gerlant van Berlaer
Varying Presentations of Multisystem Inflammatory Syndrome Temporarily Associated with COVID-19
Case Reports in Pediatrics
author_facet Jasmina Krikilion
Lisa Nuyttens
Siel Daelemans
Karlien François
Reiner Mauel
Daniel De Wolf
Gerlant van Berlaer
author_sort Jasmina Krikilion
title Varying Presentations of Multisystem Inflammatory Syndrome Temporarily Associated with COVID-19
title_short Varying Presentations of Multisystem Inflammatory Syndrome Temporarily Associated with COVID-19
title_full Varying Presentations of Multisystem Inflammatory Syndrome Temporarily Associated with COVID-19
title_fullStr Varying Presentations of Multisystem Inflammatory Syndrome Temporarily Associated with COVID-19
title_full_unstemmed Varying Presentations of Multisystem Inflammatory Syndrome Temporarily Associated with COVID-19
title_sort varying presentations of multisystem inflammatory syndrome temporarily associated with covid-19
publisher Hindawi Limited
series Case Reports in Pediatrics
issn 2090-6803
2090-6811
publishDate 2020-01-01
description Background. A novel coronavirus identified in 2019 leads to a pandemic of severe acute respiratory distress syndrome with important morbidity and mortality. Initially, children seemed minimally affected, but there were reports of cases similar to (atypical) Kawasaki disease or toxic shock syndrome, and evidence emerges about a complication named paediatric inflammatory multisystem syndrome temporarily associated with SARS-CoV-2 (PIMS-TS) or multisystem inflammatory syndrome in children (MIS-C). Case Presentations. Two cases were compared and discussed demonstrating varying presentations, management, and evolution of MIS-C. These cases are presented to increase awareness and familiarity among paediatricians and emergency physicians with the different clinical manifestations of this syndrome. Discussion. MIS-C may occur with possible diverse clinical presentations. Early recognition and treatment are paramount for a beneficial outcome.
url http://dx.doi.org/10.1155/2020/8878946
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