Endoscopic Submucosal Dissection Followed by Concurrent Chemoradiotherapy in Patients with Early Esophageal Cancer with a High Risk of Lymph Node Metastasis

Endoscopic Submucosal Dissection Followed by Concurrent Chemoradiotherapy in Patients with Early Esophageal Cancer with a High Risk of Lymph Node Metastasis

Endoscopic submucosal dissection is recommended as an alternative therapy for early esophageal cancer. However, achieving curative resection in this procedure remains controversial since precise prediction of lymph node metastasis can be difficult. Here, we present the preliminary results of endosco...

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Main Authors: Hee Kyung Kim, Weon Jin Ko, Chang-Il Kwon, Ga Won Song, In Kyun Yoo, Ji Hyun Song, Hak Su Kim, Joo Young Cho
Format: Article
Language:English
Published: Hoon Jai Chun 2019-09-01
Series:Clinical Endoscopy
Subjects:
Early esophageal cancer
Concurrent chemoradiotherapy
Endoscopic submucosal dissection
Online Access:http://www.e-ce.org/upload/pdf/ce-2018-176.pdf
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spelling doaj-b236e86f836c4d33963433d7cad3af9b2020-11-25T02:29:03ZengHoon Jai ChunClinical Endoscopy2234-24002234-24432019-09-0152550250510.5946/ce.2018.1767214Endoscopic Submucosal Dissection Followed by Concurrent Chemoradiotherapy in Patients with Early Esophageal Cancer with a High Risk of Lymph Node MetastasisHee Kyung Kim0Weon Jin Ko1Chang-Il Kwon2Ga Won Song3In Kyun Yoo4Ji Hyun Song5Hak Su Kim6Joo Young Cho7 Digestive Disease Center, CHA Bundang Medical Center, CHA University, Seongnam, Korea Digestive Disease Center, CHA Bundang Medical Center, CHA University, Seongnam, Korea Digestive Disease Center, CHA Bundang Medical Center, CHA University, Seongnam, Korea Digestive Disease Center, CHA Bundang Medical Center, CHA University, Seongnam, Korea Digestive Disease Center, CHA Bundang Medical Center, CHA University, Seongnam, Korea Digestive Disease Center, CHA Bundang Medical Center, CHA University, Seongnam, Korea Digestive Disease Center, CHA Bundang Medical Center, CHA University, Seongnam, Korea Digestive Disease Center, CHA Bundang Medical Center, CHA University, Seongnam, KoreaEndoscopic submucosal dissection is recommended as an alternative therapy for early esophageal cancer. However, achieving curative resection in this procedure remains controversial since precise prediction of lymph node metastasis can be difficult. Here, we present the preliminary results of endoscopic submucosal dissection followed by concurrent chemoradiotherapy for early esophageal cancer with a high risk of lymph node metastasis. From May 2006 to January 2014, six patients underwent concurrent chemoradiotherapy after endoscopic submucosal dissection with a median follow-up period of 63 months. No complications were encountered during concurrent chemoradiotherapy. Although local recurrence did not occur in all patients, two patients were diagnosed with metachronous cancer. Overall, the survival rate was 100%. Thus, endoscopic submucosal dissection followed by concurrent chemoradiotherapy may be a feasible treatment for early esophageal cancer in patients with a high risk of lymph node metastasis. Future prospective large-scale studies are warranted to confirm our results.http://www.e-ce.org/upload/pdf/ce-2018-176.pdfEarly esophageal cancerConcurrent chemoradiotherapyEndoscopic submucosal dissection
collection DOAJ
language English
format Article
sources DOAJ
author Hee Kyung Kim
Weon Jin Ko
Chang-Il Kwon
Ga Won Song
In Kyun Yoo
Ji Hyun Song
Hak Su Kim
Joo Young Cho
spellingShingle Hee Kyung Kim
Weon Jin Ko
Chang-Il Kwon
Ga Won Song
In Kyun Yoo
Ji Hyun Song
Hak Su Kim
Joo Young Cho
Endoscopic Submucosal Dissection Followed by Concurrent Chemoradiotherapy in Patients with Early Esophageal Cancer with a High Risk of Lymph Node Metastasis
Clinical Endoscopy
Early esophageal cancer
Concurrent chemoradiotherapy
Endoscopic submucosal dissection
author_facet Hee Kyung Kim
Weon Jin Ko
Chang-Il Kwon
Ga Won Song
In Kyun Yoo
Ji Hyun Song
Hak Su Kim
Joo Young Cho
author_sort Hee Kyung Kim
title Endoscopic Submucosal Dissection Followed by Concurrent Chemoradiotherapy in Patients with Early Esophageal Cancer with a High Risk of Lymph Node Metastasis
title_short Endoscopic Submucosal Dissection Followed by Concurrent Chemoradiotherapy in Patients with Early Esophageal Cancer with a High Risk of Lymph Node Metastasis
title_full Endoscopic Submucosal Dissection Followed by Concurrent Chemoradiotherapy in Patients with Early Esophageal Cancer with a High Risk of Lymph Node Metastasis
title_fullStr Endoscopic Submucosal Dissection Followed by Concurrent Chemoradiotherapy in Patients with Early Esophageal Cancer with a High Risk of Lymph Node Metastasis
title_full_unstemmed Endoscopic Submucosal Dissection Followed by Concurrent Chemoradiotherapy in Patients with Early Esophageal Cancer with a High Risk of Lymph Node Metastasis
title_sort endoscopic submucosal dissection followed by concurrent chemoradiotherapy in patients with early esophageal cancer with a high risk of lymph node metastasis
publisher Hoon Jai Chun
series Clinical Endoscopy
issn 2234-2400
2234-2443
publishDate 2019-09-01
description Endoscopic submucosal dissection is recommended as an alternative therapy for early esophageal cancer. However, achieving curative resection in this procedure remains controversial since precise prediction of lymph node metastasis can be difficult. Here, we present the preliminary results of endoscopic submucosal dissection followed by concurrent chemoradiotherapy for early esophageal cancer with a high risk of lymph node metastasis. From May 2006 to January 2014, six patients underwent concurrent chemoradiotherapy after endoscopic submucosal dissection with a median follow-up period of 63 months. No complications were encountered during concurrent chemoradiotherapy. Although local recurrence did not occur in all patients, two patients were diagnosed with metachronous cancer. Overall, the survival rate was 100%. Thus, endoscopic submucosal dissection followed by concurrent chemoradiotherapy may be a feasible treatment for early esophageal cancer in patients with a high risk of lymph node metastasis. Future prospective large-scale studies are warranted to confirm our results.
topic Early esophageal cancer
Concurrent chemoradiotherapy
Endoscopic submucosal dissection
url http://www.e-ce.org/upload/pdf/ce-2018-176.pdf
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