Asiatic acid inhibits pro-angiogenic effects of VEGF and human gliomas in endothelial cell culture models.

Malignant gliomas are one of the most devastating and incurable tumors. Sustained excessive angiogenesis by glioma cells is the major reason for their uncontrolled growth and resistance toward conventional therapies resulting in high mortality. Therefore, targeting angiogenesis should be a logical s...

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Bibliographic Details
Main Authors: Chandagirikoppal V Kavitha, Chapla Agarwal, Rajesh Agarwal, Gagan Deep
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3149605?pdf=render