Influence of Genistein on Hepatic Lipid Metabolism in an In Vitro Model of Hepatic Steatosis

Influence of Genistein on Hepatic Lipid Metabolism in an In Vitro Model of Hepatic Steatosis

Nonalcoholic fatty liver disease (NAFLD) is among the leading causes of end-stage liver disease. The impaired hepatic lipid metabolism in NAFLD is exhibited by dysregulated PPARα and SREBP-1c signaling pathways, which are central transcription factors associated with lipid degradation and de novo li...

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Bibliographic Details
Main Authors: Lena Seidemann, Anne Krüger, Victoria Kegel-Hübner, Daniel Seehofer, Georg Damm
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Molecules
Subjects:
liver
primary human hepatocytes
steatosis
NAFLD
NASH
Genistein
Online Access:https://www.mdpi.com/1420-3049/26/4/1156

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