Boosting Hematopoietic Engraftment after in Utero Transplantation through Vascular Niche Manipulation

Boosting Hematopoietic Engraftment after in Utero Transplantation through Vascular Niche Manipulation

Summary: In utero hematopoietic stem/progenitor cell transplantation (IUHSCT) has only been fully successful in the treatment of congenital immunodeficiency diseases. Using sheep as a large animal model of IUHSCT, we demonstrate that administration of CD146+CXCL12+VEGFR2+ or CD146+CXCL12+VEGFR2− cel...

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Bibliographic Details
Main Authors: Saloomeh Mokhtari, Evan J. Colletti, Anthony Atala, Esmail D. Zanjani, Christopher D. Porada, Graça Almeida-Porada
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671116300649

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