Injury-associated PACAP expression in rat sensory and motor neurons is induced by endogenous BDNF.

Peripheral nerve injury results in dramatic upregulation in pituitary adenylate cyclase activating polypeptide (PACAP) expression in adult rat dorsal root ganglia and spinal motor neurons mirroring that described for the neurotrophin brain derived neurotrophic factor (BDNF). Thus, we posited that in...

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Bibliographic Details
Main Authors: Lina M E Pettersson, Nicole M Geremia, Zhengxin Ying, Valerie M K Verge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4072603?pdf=render