Effect of Tongxinluo on Podocyte Apoptosis via Inhibition of Oxidative Stress and P38 Pathway in Diabetic Rats

Diabetic nephropathy (DN) has been the leading cause of end-stage renal disease (ESRD). Podocyte apoptosis is a main mechanism of progression of DN. It has been demonstrated that activated P38 and caspase-3 induced by oxidative stress mainly account for increased podocyte apoptosis and proteinuria i...

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Bibliographic Details
Main Authors: Fangqiang Cui, Yanbin Gao, Wenjing Zhao, Dawei Zou, Zhiyao Zhu, Xiaoming Wu, Nianxiu Tian, Xiaolei Wang, Jing Liu, Yu Tong
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2016/5957423