Arginase activities and global arginine bioavailability in wild-type and ApoE-deficient mice: responses to high fat and high cholesterol diets.

Arginase activities and global arginine bioavailability in wild-type and ApoE-deficient mice: responses to high fat and high cholesterol diets.

Increased catabolism of arginine by arginase is increasingly viewed as an important pathophysiological factor in cardiovascular disease, including atherosclerosis induced by high cholesterol diets. Whereas previous studies have focused primarily on effects of high cholesterol diets on arginase expre...

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Bibliographic Details
Main Authors: Aaron Erdely, Diane Kepka-Lenhart, Rebecca Salmen-Muniz, Rebecca Chapman, Tracy Hulderman, Michael Kashon, Petia P Simeonova, Sidney M Morris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2997799?pdf=render

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