Cyclic AMP-response element regulated cell cycle arrests in cancer cells.

Cyclic AMP-response element regulated cell cycle arrests in cancer cells.

Recently, we have demonstrated that trichosanthin (TCS), a promising agent for the treatment of cervical adenocarcinoma, inhibited HeLa cell proliferation through the PKC/MAPK/CREB signal pathway. Furthermore, TCS down-regulated Bcl-2 expression was abrogated by a decoy oligonucleotide (OGN) to the...

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Bibliographic Details
Main Authors:	Ping Wang, Shuaishuai Huang, Feng Wang, Yu Ren, Michael Hehir, Xue Wang, Jie Cai
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3696002?pdf=render

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