High β-1,4-Galactosyltransferase-I expression in peripheral T-lymphocytes is associated with a low risk of relapse in germ-cell cancer patients receiving high-dose chemotherapy with autologous stem cell reinfusion

High β-1,4-Galactosyltransferase-I expression in peripheral T-lymphocytes is associated with a low risk of relapse in germ-cell cancer patients receiving high-dose chemotherapy with autologous stem cell reinfusion

Survival of patients with germ-cell cancer (GCC) and primary progression or relapse after cisplatin-based first-line chemotherapy is highly heterogeneous, ranging from close to zero to more than 70%. We investigated β-1,4-Galactosyltransferase-I (B4GALT1) expression levels in peripheral lymphocytes...

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Bibliographic Details
Main Authors: Verena Nilius, Madeleine C. Killer, Nina Timmesfeld, Melina Schmitt, Roland Moll, Anja Lorch, Jörg Beyer, Elisabeth Mack, Michael Lohoff, Andreas Burchert, Andreas Neubauer, Cornelia Brendel
Format: Article
Language:English
Published: Taylor & Francis Group 2018-05-01
Series:OncoImmunology
Subjects:
b4galt1
biomarker
immunosurveillance
germ-cell cancer
t-lymphocytes
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1423169

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