Epigenetic alterations of the Wnt signaling pathway in cancer: a mini review
Epigenetic mechanisms play a crucial role in cellular proliferation, migration and differentiation in both normal and neoplastic development. One of the key signaling pathways whose components are altered through the epigenetic mechanisms is the Wnt signaling pathway. In this review, we briefly dis...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2014-11-01
|
| Series: | Bosnian Journal of Basic Medical Sciences |
| Subjects: | |
| Online Access: | http://www.bjbms.org/ojs/index.php/bjbms/article/view/205 |
| Summary: | Epigenetic mechanisms play a crucial role in cellular proliferation, migration and differentiation in both normal and neoplastic development. One of the key signaling pathways whose components are altered through the epigenetic mechanisms is the Wnt signaling pathway. In this review, we briefly discuss the key concepts of epigenetics and focus on the recent advances in the Wnt signaling pathway research and its potential diagnostic and therapeutic implications.
|
|---|---|
| ISSN: | 1512-8601 1840-4812 |