Biomimetic Human Tissue Model for Long-Term Study of Neisseria gonorrhoeae Infection

Biomimetic Human Tissue Model for Long-Term Study of Neisseria gonorrhoeae Infection

Gonorrhea is the second most common sexually transmitted infection in the world and is caused by Gram-negative diplococcus Neisseria gonorrhoeae. Since N. gonorrhoeae is a human-specific pathogen, animal infection models are only of limited use. Therefore, a suitable in vitro cell culture model for...

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Bibliographic Details
Main Authors: Motaharehsadat Heydarian, Tao Yang, Matthias Schweinlin, Maria Steinke, Heike Walles, Thomas Rudel, Vera Kozjak-Pavlovic
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Microbiology
Subjects:
3D tissue model
Neisseria gonorrhoeae
small intestinal submucosa scaffold
co-culture
infection
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01740/full

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