Mboat7 down-regulation by hyper-insulinemia induces fat accumulation in hepatocytes

Mboat7 down-regulation by hyper-insulinemia induces fat accumulation in hepatocytes

Background: Naturally occurring variation in Membrane-bound O-acyltransferase domain-containing 7 (MBOAT7), encoding for an enzyme involved in phosphatidylinositol acyl-chain remodelling, has been associated with fatty liver and hepatic disorders. Here, we examined the relationship between hepatic M...

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Main Authors: Marica Meroni, Paola Dongiovanni, Miriam Longo, Fabrizia Carli, Guido Baselli, Raffaela Rametta, Serena Pelusi, Sara Badiali, Marco Maggioni, Melania Gaggini, Anna Ludovica Fracanzani, Stefano Romeo, Stefano Gatti, Nicholas O. Davidson, Amalia Gastaldelli, Luca Valenti
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420300335

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http://www.sciencedirect.com/science/article/pii/S2352396420300335

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