Harnessing the Natural Biology of Adeno-Associated Virus to Enhance the Efficacy of Cancer Gene Therapy

Harnessing the Natural Biology of Adeno-Associated Virus to Enhance the Efficacy of Cancer Gene Therapy

Adeno-associated virus (AAV) was first characterized as small “defective” contaminant particles in a simian adenovirus preparation in 1965. Since then, a recombinant platform of AAV (rAAV) has become one of the leading candidates for gene therapy applications resulting in two FDA-approved treatments...

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Bibliographic Details
Main Authors: Jacquelyn J. Bower, Liujiang Song, Prabhakar Bastola, Matthew L. Hirsch
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Viruses
Subjects:
adeno-associated virus
AAV
cancer gene therapy
Online Access:https://www.mdpi.com/1999-4915/13/7/1205

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