Purtscher-Like Retinopathy

Purtscher-like retinopathy is associated with retinal hemorrhages and ischaemia probably due to the complement-mediated leukoembolization. It is a rare and severe angiopathy found in conditions such as acute pancreatitis. Case. We present a case of a 53-year-old man who presented with a Purtscher-li...

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Main Authors: Rita Massa, Carolina Vale, Mafalda Macedo, Maria João Furtado, Miguel Gomes, Miguel Lume, Angelina Meireles
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2015/421329
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spelling doaj-b1e5e7a4ae194cd2b6ad31d59f149fa72020-11-24T21:34:35ZengHindawi LimitedCase Reports in Ophthalmological Medicine2090-67222090-67302015-01-01201510.1155/2015/421329421329Purtscher-Like RetinopathyRita Massa0Carolina Vale1Mafalda Macedo2Maria João Furtado3Miguel Gomes4Miguel Lume5Angelina Meireles6Department of Ophthalmology, Hospital de Santo António, Centro Hospitalar do Porto, Largo Professor Abel Salazar, 4099-001 Porto, PortugalDepartment of Ophthalmology, Hospital de Santo António, Centro Hospitalar do Porto, Largo Professor Abel Salazar, 4099-001 Porto, PortugalDepartment of Ophthalmology, Hospital de Santo António, Centro Hospitalar do Porto, Largo Professor Abel Salazar, 4099-001 Porto, PortugalDepartment of Ophthalmology, Hospital de Santo António, Centro Hospitalar do Porto, Largo Professor Abel Salazar, 4099-001 Porto, PortugalDepartment of Ophthalmology, Hospital de Santo António, Centro Hospitalar do Porto, Largo Professor Abel Salazar, 4099-001 Porto, PortugalDepartment of Ophthalmology, Hospital de Santo António, Centro Hospitalar do Porto, Largo Professor Abel Salazar, 4099-001 Porto, PortugalDepartment of Ophthalmology, Hospital de Santo António, Centro Hospitalar do Porto, Largo Professor Abel Salazar, 4099-001 Porto, PortugalPurtscher-like retinopathy is associated with retinal hemorrhages and ischaemia probably due to the complement-mediated leukoembolization. It is a rare and severe angiopathy found in conditions such as acute pancreatitis. Case. We present a case of a 53-year-old man who presented with a Purtscher-like retinopathy associated with the development of acute pancreatitis in the context of a Klatskin tumour (a hilar cholangiocarcinoma). The ophthalmologic evaluation revealed the best corrected visual acuity (BCVA) of 20/32 in the right eye (RE) and of 20/40 in the left eye (LE); biomicroscopy of anterior segment showed scleral icterus and fundoscopy revealed peripapillary cotton-wool spots, optic disc edema, and RPE hypo- and hyperpigmentation in the middle peripheral retina in both eyes with an intraretinal hemorrhage in the LE. 15 months after the initial presentation, without ophthalmological treatment, there was an improvement of BCVA to 20/20 in both eyes and optical coherence tomography (OCT) revealed areas of reduction of retinal nerve fiber layer thickness corresponding to the previous cotton-wool spots. Conclusion. Purtscher-like retinopathy should not be neglected in complex clinical contexts. Its unclear pathophysiology determines an uncertain treatment strategy, but a meticulous follow-up is compulsory in order to avoid its severe complications.http://dx.doi.org/10.1155/2015/421329
collection DOAJ
language English
format Article
sources DOAJ
author Rita Massa
Carolina Vale
Mafalda Macedo
Maria João Furtado
Miguel Gomes
Miguel Lume
Angelina Meireles
spellingShingle Rita Massa
Carolina Vale
Mafalda Macedo
Maria João Furtado
Miguel Gomes
Miguel Lume
Angelina Meireles
Purtscher-Like Retinopathy
Case Reports in Ophthalmological Medicine
author_facet Rita Massa
Carolina Vale
Mafalda Macedo
Maria João Furtado
Miguel Gomes
Miguel Lume
Angelina Meireles
author_sort Rita Massa
title Purtscher-Like Retinopathy
title_short Purtscher-Like Retinopathy
title_full Purtscher-Like Retinopathy
title_fullStr Purtscher-Like Retinopathy
title_full_unstemmed Purtscher-Like Retinopathy
title_sort purtscher-like retinopathy
publisher Hindawi Limited
series Case Reports in Ophthalmological Medicine
issn 2090-6722
2090-6730
publishDate 2015-01-01
description Purtscher-like retinopathy is associated with retinal hemorrhages and ischaemia probably due to the complement-mediated leukoembolization. It is a rare and severe angiopathy found in conditions such as acute pancreatitis. Case. We present a case of a 53-year-old man who presented with a Purtscher-like retinopathy associated with the development of acute pancreatitis in the context of a Klatskin tumour (a hilar cholangiocarcinoma). The ophthalmologic evaluation revealed the best corrected visual acuity (BCVA) of 20/32 in the right eye (RE) and of 20/40 in the left eye (LE); biomicroscopy of anterior segment showed scleral icterus and fundoscopy revealed peripapillary cotton-wool spots, optic disc edema, and RPE hypo- and hyperpigmentation in the middle peripheral retina in both eyes with an intraretinal hemorrhage in the LE. 15 months after the initial presentation, without ophthalmological treatment, there was an improvement of BCVA to 20/20 in both eyes and optical coherence tomography (OCT) revealed areas of reduction of retinal nerve fiber layer thickness corresponding to the previous cotton-wool spots. Conclusion. Purtscher-like retinopathy should not be neglected in complex clinical contexts. Its unclear pathophysiology determines an uncertain treatment strategy, but a meticulous follow-up is compulsory in order to avoid its severe complications.
url http://dx.doi.org/10.1155/2015/421329
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