MiRAR—miRNA Activity Reporter for Living Cells

MiRAR—miRNA Activity Reporter for Living Cells

microRNA (miRNA) activity and regulation are of increasing interest as new therapeutic targets. Traditional approaches to assess miRNA levels in cells rely on RNA sequencing or quantitative PCR. While useful, these approaches are based on RNA extraction and cannot be applied in real-time to observe...

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Bibliographic Details
Main Authors: Matthew A. Turk, Christina Z. Chung, Emad Manni, Stephanie A. Zukowski, Anish Engineer, Yasaman Badakhshi, Yumin Bi, Ilka U. Heinemann
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Genes
Subjects:
fluorescent reporter
live cell imaging
microRNA quantification
optogenetics
small molecule drug screening
Online Access:http://www.mdpi.com/2073-4425/9/6/305

Internet

http://www.mdpi.com/2073-4425/9/6/305

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