All-trans retinoic acid modulates ORMDL3 expression via transcriptional regulation.

All-trans retinoic acid modulates ORMDL3 expression via transcriptional regulation.

All-trans retinoic acid (ATRA) is an active metabolite of Vitamin A, it shows protective effects on asthma, including maintains airway epithelial integrity, inhibits asthma effector cells differentiation, modulates immune response, et al. However, the promoting effect of ATRA on Th2 response has res...

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Bibliographic Details
Main Authors: Li-Li Zhuang, Bo-Xian Huang, Jie Feng, Liang-Hua Zhu, Rui Jin, Ling-Zhi Qiu, Guo-Ping Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3812219?pdf=render

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