Detection of Microsatellite Instability via Circulating Tumor DNA and Response to Immunotherapy in Metastatic Castration-Resistant Prostate Cancer: A Case Series

Detection of Microsatellite Instability via Circulating Tumor DNA and Response to Immunotherapy in Metastatic Castration-Resistant Prostate Cancer: A Case Series

Pembrolizumab has been approved by the US Food and Drug Administration for the treatment of metastatic or unresectable solid tumors that are microsatellite instability-high (MSI-H) or mismatch repair deficient. Blood-based circulating tumor DNA (ctDNA) assays have been validated to identify tumors w...

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Bibliographic Details
Main Authors: Deepak Ravindranathan, Greta Anne Russler, Lauren Yantorni, Leylah M. Drusbosky, Mehmet Asim Bilen
Format: Article
Language:English
Published: Karger Publishers 2021-03-01
Series:Case Reports in Oncology
Subjects:
prostate cancer
immunotherapy
liquid biopsy
microsatellite instability
Online Access:https://www.karger.com/Article/FullText/512819

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