Probing the Ion Binding Site in a DNA Holliday Junction Using Förster Resonance Energy Transfer (FRET)

Probing the Ion Binding Site in a DNA Holliday Junction Using Förster Resonance Energy Transfer (FRET)

Holliday Junctions are critical DNA intermediates central to double strand break repair and homologous recombination. The junctions can adopt two general forms: open and stacked-X, which are induced by protein or ion binding. In this work, fluorescence spectroscopy, metal ion luminescence and thermo...

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Bibliographic Details
Main Authors: Jacob L. Litke, Yan Li, Laura M. Nocka, Ishita Mukerji
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:International Journal of Molecular Sciences
Subjects:
Holliday junctions
nucleic acids
FRET
ion-binding
lanthanide luminescence
Online Access:http://www.mdpi.com/1422-0067/17/3/366

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