Linking Aortic Mechanical Properties, Gene Expression and Microstructure: A New Perspective on Regional Weakening in Abdominal Aortic Aneurysms

Linking Aortic Mechanical Properties, Gene Expression and Microstructure: A New Perspective on Regional Weakening in Abdominal Aortic Aneurysms

Background: Current clinical practice for the assessment of abdominal aortic aneurysms (AAA) is based on vessel diameter and does not account for the multifactorial, heterogeneous remodeling that results in the regional weakening of the aortic wall leading to aortic growth and rupture. The present s...

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Bibliographic Details
Main Authors: Arianna Forneris, Jacob Kennard, Alina Ismaguilova, Robert D. Shepherd, Deborah Studer, Amy Bromley, Randy D. Moore, Kristina D. Rinker, Elena S. Di Martino
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Abdominal Aortic Aneurysms
RNA
Computational Fluid Dynamics
thrombus
in vivo strain
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.631790/full

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