Polymorphisms in <i>EGFR</i> Gene Predict Clinical Outcome in Unresectable Non-Small Cell Lung Cancer Treated with Radiotherapy and Platinum-Based Chemoradiotherapy

Polymorphisms in <i>EGFR</i> Gene Predict Clinical Outcome in Unresectable Non-Small Cell Lung Cancer Treated with Radiotherapy and Platinum-Based Chemoradiotherapy

For non-small cell lung cancer (NSCLC), radiotherapy (RT) and platinum-based chemotherapy (CHT) are among the main treatment options. On the other hand, radioresistance and cytotoxic drug resistance are common causes of failure. The epidermal growth factor receptor (EGFR) plays an important role in...

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Bibliographic Details
Main Authors: Dorota Butkiewicz, Małgorzata Krześniak, Agnieszka Gdowicz-Kłosok, Monika Giglok, Małgorzata Marszałek-Zeńczak, Rafał Suwiński
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
EGFR
polymorphism
lung cancer
radiotherapy
prognosis
therapy outcome
Online Access:https://www.mdpi.com/1422-0067/22/11/5605

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