Next-generation sequencing-based genomic profiling analysis reveals novel mutations for clinical diagnosis in Chinese primary epithelial ovarian cancer patients

Next-generation sequencing-based genomic profiling analysis reveals novel mutations for clinical diagnosis in Chinese primary epithelial ovarian cancer patients

Abstract Background Ovarian cancer (OC) is one of the most malignant gynecological tumors, associated with excess death rate (50–60%) in ovarian cancer patients. Particularly, among newly occurred ovarian cancer patients, 70% of clinical cases are diagnosed at the advanced stage, which definitely de...

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Bibliographic Details
Main Authors: Lei Zhang, Min Luo, Hongying Yang, Shaoyan Zhu, Xianliang Cheng, Chen Qing
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Journal of Ovarian Research
Subjects:
Epithelial ovarian cancer
Oncogenesis
Expression profiling
Pathway analysis
Online Access:http://link.springer.com/article/10.1186/s13048-019-0494-4

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