A CASE- CONTROL STUDY ON PROSTATE CANCER INRURAL POPULATION OF PAKISTAN

ABSTRACT BACKGROUND: As in many countries of the world, Prostate cancer is extremely common in Pakistan. It is the third most common malignancy among males in Pakistan. A hospital-based, case-control study was conducted in rural area of Faisalabad (Pakistan) to examine the probable risk factors of...

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Bibliographic Details
Main Authors: Muhammad Naeem Bashir, Muhammad Akram Malik, Muhammad Riaz Ahmad
Format: Article
Language:English
Published: University of Faisalabad 2015-09-01
Series:Journal of University Medical & Dental College
Subjects:
Age
Online Access:http://jumdc.com/index.php/jumdc/article/view/246
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Summary:ABSTRACT BACKGROUND: As in many countries of the world, Prostate cancer is extremely common in Pakistan. It is the third most common malignancy among males in Pakistan. A hospital-based, case-control study was conducted in rural area of Faisalabad (Pakistan) to examine the probable risk factors of prostate cancer. MATERIALS AND METHODS: This study was based on 102 prostate cancer cases and 204 normal controls. Logistic regression was used to estimate odds ratios and 95% confidence intervals to evaluate the relationship between prostate cancer and different risk factors. RESULTS: Age, family history of prostate cancer and obesity significantly increased the prostate cancer risk having odds ratios and 95% confidence interval (13.56; 5.20-35.35), (4.70;1.6513.40) and (4.26; 2.25- 8.10) respectively. On the other hand, better lifestyle (physical activity) and literacy significantly decreased the prostate cancer risk having odd ratiosand corresponding 95% confidence intervals (0.16; 0.08- 0.30)and (0.32; 0.15- 0.65) respectively. CONCLUSIONS: In the present study age, family history of prostate cancer, obesity, literacy and better lifestyle emerged as risk factors for prostate cancer in rural population of Faisalabad
ISSN:2221-7827
2310-5542