Influence of β-Glucan (Macrogard®) on Innate Immunity of Carp Fry

• Main Authors: Sych Ganna, Frost Patrick, Irnazarow Ilgiz
• Format: Article
• Language: English
• Published: Sciendo 2013-06-01
• Series: Bulletin of the Veterinary Institute in Pulawy
• Subjects: carp; β-glucan; α-2-macroglobulin; lysozyme; classical complement pathway
• Online Access: https://doi.org/10.2478/bvip-2013-0039

β-glucan (Macrogard®) was administrated to enhance the immunity and growth of Cyprinus carpio fry. The whole body homogenate of fish sampled with one week intervals during 2nd - 6th weeks post hatching was assayed for the total protein content, lysozyme activity, α-2-macroglobulin content, classical complement pathway activation, and weight gain. After the 3rd week of experimental feeding, the total protein content and the classical complement activity of fish fed β-glucan supplemented diet were higher than controls. Significantly higher lysozyme activity and α-2-macroglobulin levels were noted in group fed β-glucan at the 2nd and 3rd week of diet application. It was demonstrated that β-glucan enriched feeding increased the immunity of common carp at the earliest stages of their development.