"Pyrimethamine and Proguanil Resistance-Conferring Key Mutations in Dihydrofolate Reductase Gene of Plasmodium falciparum Isolates from Iran"

Using mutation specific PCR assay and analysis of position 108 amino acid in dihydrofolate reductase-thymidilate synthase gene in 70 Plasmodium falciparum isolates of malarial patients from southern areas of Iran, showed 4 different situations: iwild type (108-Ser) ii-mutant type (108-Thr) iii-mutan...

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Bibliographic Details
Main Authors: AA Eskandarian, H Keshavarz, F Mahboudi
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2003-10-01
Series:Iranian Journal of Public Health
Subjects:
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/145.pdf&manuscript_id=145