Microstructure, Mechanical, and Biological Properties of Porous Poly(vinylidene fluoride) Scaffolds Fabricated by Selective Laser Sintering
Porous poly(vinylidene fluoride) (PVDF) scaffolds were prepared by selective laser sintering. The effects of laser energy density, ranging from 0.66 to 2.16 J/mm2, on microstructure and mechanical properties were investigated. At low energy density levels, PVDF particles could fuse well and the stru...
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Series: | International Journal of Polymer Science |
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doaj-b179ebe68b2b4ba68a10d3ef2ec231c62020-11-24T22:38:58ZengHindawi LimitedInternational Journal of Polymer Science1687-94221687-94302015-01-01201510.1155/2015/132965132965Microstructure, Mechanical, and Biological Properties of Porous Poly(vinylidene fluoride) Scaffolds Fabricated by Selective Laser SinteringWei Huang0Pei Feng1Chengde Gao2Xiong Shuai3Tao Xiao4Cijun Shuai5Shuping Peng6Hunan Provincial Tumor Hospital and the Affiliated Tumor Hospital of Xiangya School of Medicine, Central South University, Changsha 410013, ChinaState Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha 410083, ChinaState Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha 410083, ChinaState Key Laboratory of Powder Metallurgy, Central South University, Changsha 410083, ChinaOrthopedic Biomedical Materials Institute, Central South University, Changsha 410083, ChinaState Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha 410083, ChinaHunan Provincial Tumor Hospital and the Affiliated Tumor Hospital of Xiangya School of Medicine, Central South University, Changsha 410013, ChinaPorous poly(vinylidene fluoride) (PVDF) scaffolds were prepared by selective laser sintering. The effects of laser energy density, ranging from 0.66 to 2.16 J/mm2, on microstructure and mechanical properties were investigated. At low energy density levels, PVDF particles could fuse well and the structure becomes dense with the increase of the energy density. Smoke and defects (such as holes) were observed when the energy density increased above 1.56 J/mm2 which indicated decomposition of the PVDF powder. The scaffolds appeared to be light yellow and there was a reduction in tensile strength. The fabricated scaffolds were immersed into simulated body fluid for different time to evaluate biostability. In addition, MG63 cells were seeded and cultured for different days on the scaffolds. The testing results showed that the cells grew and spread well, indicating that PVDF scaffolds had good biocompatibility.http://dx.doi.org/10.1155/2015/132965 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Wei Huang Pei Feng Chengde Gao Xiong Shuai Tao Xiao Cijun Shuai Shuping Peng |
spellingShingle |
Wei Huang Pei Feng Chengde Gao Xiong Shuai Tao Xiao Cijun Shuai Shuping Peng Microstructure, Mechanical, and Biological Properties of Porous Poly(vinylidene fluoride) Scaffolds Fabricated by Selective Laser Sintering International Journal of Polymer Science |
author_facet |
Wei Huang Pei Feng Chengde Gao Xiong Shuai Tao Xiao Cijun Shuai Shuping Peng |
author_sort |
Wei Huang |
title |
Microstructure, Mechanical, and Biological Properties of Porous Poly(vinylidene fluoride) Scaffolds Fabricated by Selective Laser Sintering |
title_short |
Microstructure, Mechanical, and Biological Properties of Porous Poly(vinylidene fluoride) Scaffolds Fabricated by Selective Laser Sintering |
title_full |
Microstructure, Mechanical, and Biological Properties of Porous Poly(vinylidene fluoride) Scaffolds Fabricated by Selective Laser Sintering |
title_fullStr |
Microstructure, Mechanical, and Biological Properties of Porous Poly(vinylidene fluoride) Scaffolds Fabricated by Selective Laser Sintering |
title_full_unstemmed |
Microstructure, Mechanical, and Biological Properties of Porous Poly(vinylidene fluoride) Scaffolds Fabricated by Selective Laser Sintering |
title_sort |
microstructure, mechanical, and biological properties of porous poly(vinylidene fluoride) scaffolds fabricated by selective laser sintering |
publisher |
Hindawi Limited |
series |
International Journal of Polymer Science |
issn |
1687-9422 1687-9430 |
publishDate |
2015-01-01 |
description |
Porous poly(vinylidene fluoride) (PVDF) scaffolds were prepared by selective laser sintering. The effects of laser energy density, ranging from 0.66 to 2.16 J/mm2, on microstructure and mechanical properties were investigated. At low energy density levels, PVDF particles could fuse well and the structure becomes dense with the increase of the energy density. Smoke and defects (such as holes) were observed when the energy density increased above 1.56 J/mm2 which indicated decomposition of the PVDF powder. The scaffolds appeared to be light yellow and there was a reduction in tensile strength. The fabricated scaffolds were immersed into simulated body fluid for different time to evaluate biostability. In addition, MG63 cells were seeded and cultured for different days on the scaffolds. The testing results showed that the cells grew and spread well, indicating that PVDF scaffolds had good biocompatibility. |
url |
http://dx.doi.org/10.1155/2015/132965 |
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