Microstructure, Mechanical, and Biological Properties of Porous Poly(vinylidene fluoride) Scaffolds Fabricated by Selective Laser Sintering

Porous poly(vinylidene fluoride) (PVDF) scaffolds were prepared by selective laser sintering. The effects of laser energy density, ranging from 0.66 to 2.16 J/mm2, on microstructure and mechanical properties were investigated. At low energy density levels, PVDF particles could fuse well and the stru...

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Main Authors: Wei Huang, Pei Feng, Chengde Gao, Xiong Shuai, Tao Xiao, Cijun Shuai, Shuping Peng
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:International Journal of Polymer Science
Online Access:http://dx.doi.org/10.1155/2015/132965
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spelling doaj-b179ebe68b2b4ba68a10d3ef2ec231c62020-11-24T22:38:58ZengHindawi LimitedInternational Journal of Polymer Science1687-94221687-94302015-01-01201510.1155/2015/132965132965Microstructure, Mechanical, and Biological Properties of Porous Poly(vinylidene fluoride) Scaffolds Fabricated by Selective Laser SinteringWei Huang0Pei Feng1Chengde Gao2Xiong Shuai3Tao Xiao4Cijun Shuai5Shuping Peng6Hunan Provincial Tumor Hospital and the Affiliated Tumor Hospital of Xiangya School of Medicine, Central South University, Changsha 410013, ChinaState Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha 410083, ChinaState Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha 410083, ChinaState Key Laboratory of Powder Metallurgy, Central South University, Changsha 410083, ChinaOrthopedic Biomedical Materials Institute, Central South University, Changsha 410083, ChinaState Key Laboratory of High Performance Complex Manufacturing, Central South University, Changsha 410083, ChinaHunan Provincial Tumor Hospital and the Affiliated Tumor Hospital of Xiangya School of Medicine, Central South University, Changsha 410013, ChinaPorous poly(vinylidene fluoride) (PVDF) scaffolds were prepared by selective laser sintering. The effects of laser energy density, ranging from 0.66 to 2.16 J/mm2, on microstructure and mechanical properties were investigated. At low energy density levels, PVDF particles could fuse well and the structure becomes dense with the increase of the energy density. Smoke and defects (such as holes) were observed when the energy density increased above 1.56 J/mm2 which indicated decomposition of the PVDF powder. The scaffolds appeared to be light yellow and there was a reduction in tensile strength. The fabricated scaffolds were immersed into simulated body fluid for different time to evaluate biostability. In addition, MG63 cells were seeded and cultured for different days on the scaffolds. The testing results showed that the cells grew and spread well, indicating that PVDF scaffolds had good biocompatibility.http://dx.doi.org/10.1155/2015/132965
collection DOAJ
language English
format Article
sources DOAJ
author Wei Huang
Pei Feng
Chengde Gao
Xiong Shuai
Tao Xiao
Cijun Shuai
Shuping Peng
spellingShingle Wei Huang
Pei Feng
Chengde Gao
Xiong Shuai
Tao Xiao
Cijun Shuai
Shuping Peng
Microstructure, Mechanical, and Biological Properties of Porous Poly(vinylidene fluoride) Scaffolds Fabricated by Selective Laser Sintering
International Journal of Polymer Science
author_facet Wei Huang
Pei Feng
Chengde Gao
Xiong Shuai
Tao Xiao
Cijun Shuai
Shuping Peng
author_sort Wei Huang
title Microstructure, Mechanical, and Biological Properties of Porous Poly(vinylidene fluoride) Scaffolds Fabricated by Selective Laser Sintering
title_short Microstructure, Mechanical, and Biological Properties of Porous Poly(vinylidene fluoride) Scaffolds Fabricated by Selective Laser Sintering
title_full Microstructure, Mechanical, and Biological Properties of Porous Poly(vinylidene fluoride) Scaffolds Fabricated by Selective Laser Sintering
title_fullStr Microstructure, Mechanical, and Biological Properties of Porous Poly(vinylidene fluoride) Scaffolds Fabricated by Selective Laser Sintering
title_full_unstemmed Microstructure, Mechanical, and Biological Properties of Porous Poly(vinylidene fluoride) Scaffolds Fabricated by Selective Laser Sintering
title_sort microstructure, mechanical, and biological properties of porous poly(vinylidene fluoride) scaffolds fabricated by selective laser sintering
publisher Hindawi Limited
series International Journal of Polymer Science
issn 1687-9422
1687-9430
publishDate 2015-01-01
description Porous poly(vinylidene fluoride) (PVDF) scaffolds were prepared by selective laser sintering. The effects of laser energy density, ranging from 0.66 to 2.16 J/mm2, on microstructure and mechanical properties were investigated. At low energy density levels, PVDF particles could fuse well and the structure becomes dense with the increase of the energy density. Smoke and defects (such as holes) were observed when the energy density increased above 1.56 J/mm2 which indicated decomposition of the PVDF powder. The scaffolds appeared to be light yellow and there was a reduction in tensile strength. The fabricated scaffolds were immersed into simulated body fluid for different time to evaluate biostability. In addition, MG63 cells were seeded and cultured for different days on the scaffolds. The testing results showed that the cells grew and spread well, indicating that PVDF scaffolds had good biocompatibility.
url http://dx.doi.org/10.1155/2015/132965
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