A Rare Case of Severe Lactic Acidosis in a Patient With Mantle Cell Lymphoma

Lactic acidosis is an extremely rare paraneoplastic manifestation of hematological malignancies, and often carries an extremely poor prognosis. Mantle cell lymphoma is an aggressive and rare form of non-Hodgkin lymphoma. To the best of our knowledge, it is extremely rare to have severe lactic acidos...

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Main Authors:	Kok Hoe Chan MD, Laxminarayan Prabhakar MD, Omar Al-Radideh MD, Byron Okwesili MD, Gowthami Are MD, Hamid Shaaban MD
Format:	Article
Language:	English
Published:	SAGE Publishing 2021-07-01
Series:	Journal of Investigative Medicine High Impact Case Reports
Online Access:	https://doi.org/10.1177/23247096211034040

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spelling	doaj-b1772574f8dd4bb18cc8d31ec16ec4cb2021-07-31T21:34:23ZengSAGE PublishingJournal of Investigative Medicine High Impact Case Reports2324-70962021-07-01910.1177/23247096211034040A Rare Case of Severe Lactic Acidosis in a Patient With Mantle Cell LymphomaKok Hoe Chan MD0Laxminarayan Prabhakar MD1Omar Al-Radideh MD2Byron Okwesili MD3Gowthami Are MD4Hamid Shaaban MD5Saint Michael’s Medical Center, New York Medical College, Newark, NJ, USASaint Michael’s Medical Center, New York Medical College, Newark, NJ, USASaint Michael’s Medical Center, New York Medical College, Newark, NJ, USASaint Michael’s Medical Center, New York Medical College, Newark, NJ, USASaint Michael’s Medical Center, New York Medical College, Newark, NJ, USASaint Michael’s Medical Center, New York Medical College, Newark, NJ, USALactic acidosis is an extremely rare paraneoplastic manifestation of hematological malignancies, and often carries an extremely poor prognosis. Mantle cell lymphoma is an aggressive and rare form of non-Hodgkin lymphoma. To the best of our knowledge, it is extremely rare to have severe lactic acidosis in patients with mantle cell lymphoma. In this article, we are reporting a rare case of mantle cell lymphoma diagnosed with typical cluster differentiation (CD markers) in bone marrow examination with persistent lactic acidosis refractory to intravenous hydration that responded well to chemotherapy. Malignant lactic acidosis is a medical emergency that needs rapid evaluation and identification that shows improved prognosis after the introduction of chemotherapy.https://doi.org/10.1177/23247096211034040
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Kok Hoe Chan MD Laxminarayan Prabhakar MD Omar Al-Radideh MD Byron Okwesili MD Gowthami Are MD Hamid Shaaban MD
spellingShingle	Kok Hoe Chan MD Laxminarayan Prabhakar MD Omar Al-Radideh MD Byron Okwesili MD Gowthami Are MD Hamid Shaaban MD A Rare Case of Severe Lactic Acidosis in a Patient With Mantle Cell Lymphoma Journal of Investigative Medicine High Impact Case Reports
author_facet	Kok Hoe Chan MD Laxminarayan Prabhakar MD Omar Al-Radideh MD Byron Okwesili MD Gowthami Are MD Hamid Shaaban MD
author_sort	Kok Hoe Chan MD
title	A Rare Case of Severe Lactic Acidosis in a Patient With Mantle Cell Lymphoma
title_short	A Rare Case of Severe Lactic Acidosis in a Patient With Mantle Cell Lymphoma
title_full	A Rare Case of Severe Lactic Acidosis in a Patient With Mantle Cell Lymphoma
title_fullStr	A Rare Case of Severe Lactic Acidosis in a Patient With Mantle Cell Lymphoma
title_full_unstemmed	A Rare Case of Severe Lactic Acidosis in a Patient With Mantle Cell Lymphoma
title_sort	rare case of severe lactic acidosis in a patient with mantle cell lymphoma
publisher	SAGE Publishing
series	Journal of Investigative Medicine High Impact Case Reports
issn	2324-7096
publishDate	2021-07-01
description	Lactic acidosis is an extremely rare paraneoplastic manifestation of hematological malignancies, and often carries an extremely poor prognosis. Mantle cell lymphoma is an aggressive and rare form of non-Hodgkin lymphoma. To the best of our knowledge, it is extremely rare to have severe lactic acidosis in patients with mantle cell lymphoma. In this article, we are reporting a rare case of mantle cell lymphoma diagnosed with typical cluster differentiation (CD markers) in bone marrow examination with persistent lactic acidosis refractory to intravenous hydration that responded well to chemotherapy. Malignant lactic acidosis is a medical emergency that needs rapid evaluation and identification that shows improved prognosis after the introduction of chemotherapy.
url	https://doi.org/10.1177/23247096211034040
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A Rare Case of Severe Lactic Acidosis in a Patient With Mantle Cell Lymphoma

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