Suppressing glucose uptake and acetic acid production increases membrane protein overexpression in <it>Escherichia coli</it>
<p>Abstract</p> <p>Background</p> <p>The production of integral membrane spanning proteins (IMP's) constitutes a bottleneck in pharmaceutical development. It was long considered that the state-of-the-art was to produce the proteins as inclusion bodies using a power...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-05-01
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Series: | Microbial Cell Factories |
Online Access: | http://www.microbialcellfactories.com/content/10/1/35 |