Suppressing glucose uptake and acetic acid production increases membrane protein overexpression in <it>Escherichia coli</it>

<p>Abstract</p> <p>Background</p> <p>The production of integral membrane spanning proteins (IMP's) constitutes a bottleneck in pharmaceutical development. It was long considered that the state-of-the-art was to produce the proteins as inclusion bodies using a power...

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Bibliographic Details
Main Authors: Larsson Gen, Ignatushchenko Marina, Bäcklund Emma
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Microbial Cell Factories
Online Access:http://www.microbialcellfactories.com/content/10/1/35