Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis

Optogenetics is opening the possibility to not only perturb morphogenesis, but also to guide it. Here, the authors use this technique to reconstruct epithelial folding in Drosophila embryos and study the relationship between strength of Rho activation, apical constrictions, and tissue invagination.

Bibliographic Details
Main Authors:	Emiliano Izquierdo, Theresa Quinkler, Stefano De Renzis
Format:	Article
Language:	English
Published:	Nature Publishing Group 2018-06-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-018-04754-z

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record_format	Article
spelling	doaj-b1741e13a0c346a59adb26660f00092b2021-05-11T09:21:46ZengNature Publishing GroupNature Communications2041-17232018-06-019111310.1038/s41467-018-04754-zGuided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesisEmiliano Izquierdo0Theresa Quinkler1Stefano De Renzis2EMBL HeidelbergEMBL HeidelbergEMBL HeidelbergOptogenetics is opening the possibility to not only perturb morphogenesis, but also to guide it. Here, the authors use this technique to reconstruct epithelial folding in Drosophila embryos and study the relationship between strength of Rho activation, apical constrictions, and tissue invagination.https://doi.org/10.1038/s41467-018-04754-z
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Emiliano Izquierdo Theresa Quinkler Stefano De Renzis
spellingShingle	Emiliano Izquierdo Theresa Quinkler Stefano De Renzis Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis Nature Communications
author_facet	Emiliano Izquierdo Theresa Quinkler Stefano De Renzis
author_sort	Emiliano Izquierdo
title	Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis
title_short	Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis
title_full	Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis
title_fullStr	Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis
title_full_unstemmed	Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis
title_sort	guided morphogenesis through optogenetic activation of rho signalling during early drosophila embryogenesis
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2018-06-01
description	Optogenetics is opening the possibility to not only perturb morphogenesis, but also to guide it. Here, the authors use this technique to reconstruct epithelial folding in Drosophila embryos and study the relationship between strength of Rho activation, apical constrictions, and tissue invagination.
url	https://doi.org/10.1038/s41467-018-04754-z
work_keys_str_mv	AT emilianoizquierdo guidedmorphogenesisthroughoptogeneticactivationofrhosignallingduringearlydrosophilaembryogenesis AT theresaquinkler guidedmorphogenesisthroughoptogeneticactivationofrhosignallingduringearlydrosophilaembryogenesis AT stefanoderenzis guidedmorphogenesisthroughoptogeneticactivationofrhosignallingduringearlydrosophilaembryogenesis
_version_	1721450020468686848

Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis

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