Genetic factors influencing HIV entry into target cells

Genetic factors influencing HIV entry into target cells

Succeptibility to HIV and the dynamics of HIV infection progression to AIDS are dependent on unique individual factors. Revealing genetic features of natural resistance to HIV infection is of great importance for the development of effective strategies for disease control. This review presents an an...

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Bibliographic Details
Main Authors: R. M. Khaitov, L. P. Alexeev, I. A. Kofiadi, G. O. Gudima
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2019-05-01
Series:Bûlleten' Sibirskoj Mediciny
Subjects:
hiv
genes
allels
pathogenesis
receptors
resistance/succeptibility to hiv infection
Online Access:https://bulletin.tomsk.ru/jour/article/view/2177
Description
Summary:Succeptibility to HIV and the dynamics of HIV infection progression to AIDS are dependent on unique individual factors. Revealing genetic features of natural resistance to HIV infection is of great importance for the development of effective strategies for disease control. This review presents an analysis of host gene alleles coding receptors and their ligands participating in viral entrance to target cell. These allelic variants and their combinations can have a significant influence on the individual resistance/sensitivity to HIV infection and may be associated with the HIV infection progression to AIDS.
ISSN:1682-0363
1819-3684

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