Patient with Down syndrome and relapsed acute lymphoblastic leukemia with sustained remission despite only partial R3 chemotherapy

Abstract DS‐ALL has a higher rate of relapse and treatment‐related mortality. The newer immunotherapies are potentially better options. Relapsed ALL with positive MRD has a poor prognosis. Transient long‐term remission after ALL relapse due to partial chemotherapy combined severe infection is rare....

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Main Authors:	Zhongbo Hu, Kristen A. VanHeyst, Jignesh Dalal, Lisa Hackney
Format:	Article
Language:	English
Published:	Wiley 2021-03-01
Series:	Clinical Case Reports
Subjects:	ALL R3 Down syndrome Relapsed acute lymphoblastic leukemia remission
Online Access:	https://doi.org/10.1002/ccr3.3678

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record_format	Article
spelling	doaj-b15dc99b32f0402bad081ff4e4bf0d0e2021-03-21T09:11:39ZengWileyClinical Case Reports2050-09042021-03-01931118112210.1002/ccr3.3678Patient with Down syndrome and relapsed acute lymphoblastic leukemia with sustained remission despite only partial R3 chemotherapyZhongbo Hu0Kristen A. VanHeyst1Jignesh Dalal2Lisa Hackney3Department of Pediatrics Division of Pediatric Hematology Oncology Rainbow Babies and Children’s Hospital at University Hospitals Cleveland Medical Center Cleveland OH USADepartment of Pediatrics Division of Pediatric Hematology Oncology Rainbow Babies and Children’s Hospital at University Hospitals Cleveland Medical Center Cleveland OH USADepartment of Pediatrics Division of Pediatric Hematology Oncology Rainbow Babies and Children’s Hospital at University Hospitals Cleveland Medical Center Cleveland OH USADepartment of Pediatrics Division of Pediatric Hematology Oncology Rainbow Babies and Children’s Hospital at University Hospitals Cleveland Medical Center Cleveland OH USAAbstract DS‐ALL has a higher rate of relapse and treatment‐related mortality. The newer immunotherapies are potentially better options. Relapsed ALL with positive MRD has a poor prognosis. Transient long‐term remission after ALL relapse due to partial chemotherapy combined severe infection is rare.https://doi.org/10.1002/ccr3.3678ALL R3Down syndromeRelapsed acute lymphoblastic leukemiaremission
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Zhongbo Hu Kristen A. VanHeyst Jignesh Dalal Lisa Hackney
spellingShingle	Zhongbo Hu Kristen A. VanHeyst Jignesh Dalal Lisa Hackney Patient with Down syndrome and relapsed acute lymphoblastic leukemia with sustained remission despite only partial R3 chemotherapy Clinical Case Reports ALL R3 Down syndrome Relapsed acute lymphoblastic leukemia remission
author_facet	Zhongbo Hu Kristen A. VanHeyst Jignesh Dalal Lisa Hackney
author_sort	Zhongbo Hu
title	Patient with Down syndrome and relapsed acute lymphoblastic leukemia with sustained remission despite only partial R3 chemotherapy
title_short	Patient with Down syndrome and relapsed acute lymphoblastic leukemia with sustained remission despite only partial R3 chemotherapy
title_full	Patient with Down syndrome and relapsed acute lymphoblastic leukemia with sustained remission despite only partial R3 chemotherapy
title_fullStr	Patient with Down syndrome and relapsed acute lymphoblastic leukemia with sustained remission despite only partial R3 chemotherapy
title_full_unstemmed	Patient with Down syndrome and relapsed acute lymphoblastic leukemia with sustained remission despite only partial R3 chemotherapy
title_sort	patient with down syndrome and relapsed acute lymphoblastic leukemia with sustained remission despite only partial r3 chemotherapy
publisher	Wiley
series	Clinical Case Reports
issn	2050-0904
publishDate	2021-03-01
description	Abstract DS‐ALL has a higher rate of relapse and treatment‐related mortality. The newer immunotherapies are potentially better options. Relapsed ALL with positive MRD has a poor prognosis. Transient long‐term remission after ALL relapse due to partial chemotherapy combined severe infection is rare.
topic	ALL R3 Down syndrome Relapsed acute lymphoblastic leukemia remission
url	https://doi.org/10.1002/ccr3.3678
work_keys_str_mv	AT zhongbohu patientwithdownsyndromeandrelapsedacutelymphoblasticleukemiawithsustainedremissiondespiteonlypartialr3chemotherapy AT kristenavanheyst patientwithdownsyndromeandrelapsedacutelymphoblasticleukemiawithsustainedremissiondespiteonlypartialr3chemotherapy AT jigneshdalal patientwithdownsyndromeandrelapsedacutelymphoblasticleukemiawithsustainedremissiondespiteonlypartialr3chemotherapy AT lisahackney patientwithdownsyndromeandrelapsedacutelymphoblasticleukemiawithsustainedremissiondespiteonlypartialr3chemotherapy
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Patient with Down syndrome and relapsed acute lymphoblastic leukemia with sustained remission despite only partial R3 chemotherapy

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