A printable hydrogel microarray for drug screening avoids false positives associated with promiscuous aggregating inhibitors

False positive results significantly slow down the drug discovery process. Here, the authors developed a gel serving as a screening platform in which enzymes can be stored, stabilized, and protected from most of the compounds that typically cause these misleading results.

Bibliographic Details
Main Authors: Rabia Mateen, M. Monsur Ali, Todd Hoare
Format: Article
Language:English
Published: Nature Publishing Group 2018-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-02956-z
Description
Summary:False positive results significantly slow down the drug discovery process. Here, the authors developed a gel serving as a screening platform in which enzymes can be stored, stabilized, and protected from most of the compounds that typically cause these misleading results.
ISSN:2041-1723