PCA3 noncoding RNA is involved in the control of prostate-cancer cell survival and modulates androgen receptor signaling

PCA3 noncoding RNA is involved in the control of prostate-cancer cell survival and modulates androgen receptor signaling

<p>Abstract</p> <p>Background</p> <p>PCA3 is a non-coding RNA (ncRNA) that is highly expressed in prostate cancer (PCa) cells, but its functional role is unknown. To investigate its putative function in PCa biology, we used gene expression knockdown by small interferenc...

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Bibliographic Details
Main Authors: Ferreira Luciana Bueno, Palumbo Antonio, de Mello Kivvi Duarte, Sternberg Cinthya, Caetano Mauricio S, de Oliveira Felipe Leite, Neves Adriana Freitas, Nasciutti Luiz Eurico, Goulart Luiz Ricardo, Gimba Etel Rodrigues Pereira
Format: Article
Language:English
Published: BMC 2012-11-01
Series:BMC Cancer
Subjects:
PCA3
Prostate cancer
Small interfering RNA
Cell survival
Noncoding RNA
Online Access:http://www.biomedcentral.com/1471-2407/12/507

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