Expression of the Bitter Taste Receptor, T2R38, in Enteroendocrine Cells of the Colonic Mucosa of Overweight/Obese vs. Lean Subjects.

Bitter taste receptors (T2Rs) are expressed in the mammalian gastrointestinal mucosa. In the mouse colon, T2R138 is localized to enteroendocrine cells and is upregulated by long-term high fat diet that induces obesity. The aims of this study were to test whether T2R38 expression is altered in overwe...

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Bibliographic Details
Main Authors: Rocco Latorre, Jennifer Huynh, Maurizio Mazzoni, Arpana Gupta, Elena Bonora, Paolo Clavenzani, Lin Chang, Emeran A Mayer, Roberto De Giorgio, Catia Sternini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4750998?pdf=render