Pharmacokinetics, Biodistribution and Toxicity Studies for Nanocarrier of Antitubercular Agent- Rifabutin

Pharmacokinetics, Biodistribution and Toxicity Studies for Nanocarrier of Antitubercular Agent- Rifabutin

Introduction: Rifabutin (RFB) is a lipophilic, semi-synthetic antibiotic given for the treatment of atypical mycobacterial infections along with drug susceptible tuberculosis infections. The major challenges in its usage include low oral bioavailability (~20%) mainly due to its low solubility an...

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Bibliographic Details
Main Authors: Swapnil Patil, SURENDRA Gattani, Pradip Nirbhavane, Kiran Patil, Amit Kumar Pal
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2020-12-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
bioavailability
mycobacterium tuberculosis
sustained release pattern
Online Access:https://jcdr.net/articles/PDF/14363/47252_CE(Ra1)_P(AK)_PF1(AD_OM)_PFA(OM)_PN(SL).pdf

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