Biostatistical Assessment of Mutagenicity Studies: A Stepwise Confidence Procedure

The paper addresses the issue of identifying the maximum safe dose in the context of noninferiority trials where several doses of toxicological compounds exist. Statistical methodology for identifying the maximum safe dose is available for three-arm noninferiority designs with only one experimental...

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Bibliographic Details
Main Authors: Michael J. Adjabui, Nathaniel K. Howard, Mathias Akamba
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Journal of Probability and Statistics
Online Access:http://dx.doi.org/10.1155/2019/3249097