Standardized extract of Centella asiatica ECa 233 inhibits lipopolysaccharide-induced cytokine release in skin keratinocytes by suppressing ERK1/2 pathways

Standardized extract of Centella asiatica ECa 233 inhibits lipopolysaccharide-induced cytokine release in skin keratinocytes by suppressing ERK1/2 pathways

Objective: To evaluate the effect of standardized extract of Centella asiatica ECa 233 on inflammatory mediator production through cyclooxygenase-2 (COX-2), extracellular signal-regulated kinase 1/2 (ERK1/2) and nuclear factor-κB (NF-κB) pathway in keratinocyte HaCaT cells. Methods: HaCaT cells were...

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Bibliographic Details
Main Authors: Furoida Moolsap, Supita Tanasawet, Mayuree H Tantisira, Pilaiwanwadee Hutamekalin, Varomyalin Tipmanee, Wanida Sukketsiri
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
centella asiatica; cyclooxygenase-2; hacat; interleukin-1β; tumor necrosis factor-α
Online Access:http://www.apjtb.org/article.asp?issn=2221-1691;year=2020;volume=10;issue=6;spage=273;epage=280;aulast=Moolsap

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