Vaccination against influenza with recombinant hemagglutinin expressed by Schizochytrium sp. confers protective immunity.
For the rapid production of influenza vaccine antigens in unlimited quantities, a transition from conventional egg-based production to cell-based and recombinant systems is required. The need for higher-yield, lower-cost, and faster production processes is critical to provide adequate supplies of in...
Main Authors: | Anne-Cécile V Bayne, David Boltz, Carole Owen, Yelena Betz, Goncalo Maia, Parastoo Azadi, Stephanie Archer-Hartmann, Ross Zirkle, J Casey Lippmeier |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3634000?pdf=render |
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