AT-MSCs Antifibrotic Activity is Improved by Eugenol through Modulation of TGF-β/Smad Signaling Pathway in Rats

AT-MSCs Antifibrotic Activity is Improved by Eugenol through Modulation of TGF-β/Smad Signaling Pathway in Rats

For hepatic failure, stem cell transplantation has been chosen as an alternative therapy, especially for mesenchymal stem cells (MSCs). The aim of this study was to investigate the effect of eugenol (EUG) on the in vivo antifibrotic activity of adipose tissue-derived MSCs (AT-MSCs) and the underlyin...

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Bibliographic Details
Main Authors: Moustafa Fathy, Motonori Okabe, Heba M. Saad Eldien, Toshiko Yoshida
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Molecules
Subjects:
at-mscs
eugenol
hepatic fibrosis
tgf-β
smad3
tnf-α
il-6
<i>α</i>-sma
Online Access:https://www.mdpi.com/1420-3049/25/2/348

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