EXPERIENCE OF TREATMENT WITH RITUXIMAB IN PATIENT WITH SYSTEMIC TYPE OF JUVENILE RHEUMATOID ARTHRITIS

The article gives a case report on patient with severe systemic type of juvenile arthritis, refractory to treatment with classical immuno suppressants and blocker of tumor necrotizing factor Successive application of biological agent — rituximab was described. In 9 weeks, extra articular symptoms of...

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Bibliographic Details
Main Authors: K.B. Isaeva, E.I. Alexeeva, R.V. Denisova, T.M. Bzarova, S.I. Valieva, A.O. Lisitsin, E.Yu. Gudkova, E.L. Semikina, E.A. Kopyl'tsova
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2009-05-01
Series:Voprosy Sovremennoj Pediatrii
Online Access:https://vsp.spr-journal.ru/jour/article/view/1131
Description
Summary:The article gives a case report on patient with severe systemic type of juvenile arthritis, refractory to treatment with classical immuno suppressants and blocker of tumor necrotizing factor Successive application of biological agent — rituximab was described. In 9 weeks, extra articular symptoms of disease and acute inflammatory lesions in joints were stopped, and functional activity of child increased. Presented case report demonstrates high effectiveness of rituximab: patient with severe systemic type of juvenile arthritis has clinical and laboratory remission of disease during 12 months.Key words: children, juvenile rheumatoid arthritis, rituximab.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(3):132-138)
ISSN:1682-5527
1682-5535