L-cell Arntl is required for rhythmic glucagon-like peptide-1 secretion and maintenance of intestinal homeostasis

L-cell Arntl is required for rhythmic glucagon-like peptide-1 secretion and maintenance of intestinal homeostasis

Objective: Recent studies using whole-body clock-disrupted animals identified a disruption in the circadian rhythm of the intestinal L-cell incretin hormone, glucagon-like peptide-1 (GLP-1). Although GLP-1 plays an essential role in metabolism through enhancement of both glucose-stimulated insulin s...

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Bibliographic Details
Main Authors: Sarah E. Martchenko, Alexandre Martchenko, Andrew D. Biancolin, Alison Waller, Patricia L. Brubaker
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Molecular Metabolism
Subjects:
Circadian
Colon
GLP-1
GLP-2
Immunity
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877821001873

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http://www.sciencedirect.com/science/article/pii/S2212877821001873

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