High-Grade Serous Tumor Arising from Fallopian Tube in a BRCA Mutation Carrier after Prophylactic Oophorectomy

High-Grade Serous Tumor Arising from Fallopian Tube in a BRCA Mutation Carrier after Prophylactic Oophorectomy

We present the case of a 67-year-old patient with a BRCA1 mutation and breast cancer who underwent prophylactic oophorectomy. After 6 years, an abdominal computed tomography revealed a pelvic mass which proved to be a poorly differentiated serous carcinoma originating from the right residual tube wh...

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Bibliographic Details
Main Authors: Domenica Lorusso, Roberta Di Rocco, Maria Mancini, Francesco Raspagliesi
Format: Article
Language:English
Published: Karger Publishers 2013-01-01
Series:Case Reports in Oncology
Subjects:
Ovarian cancer
Fallopian tube
BRCA mutation
Kurman’s hypothesis
Online Access:http://www.karger.com/Article/FullText/346339
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spelling doaj-b1233e22984445cebbcae3d900644e112020-11-25T01:50:38ZengKarger PublishersCase Reports in Oncology1662-65752013-01-0161212410.1159/000346339346339High-Grade Serous Tumor Arising from Fallopian Tube in a BRCA Mutation Carrier after Prophylactic OophorectomyDomenica LorussoRoberta Di RoccoMaria ManciniFrancesco RaspagliesiWe present the case of a 67-year-old patient with a BRCA1 mutation and breast cancer who underwent prophylactic oophorectomy. After 6 years, an abdominal computed tomography revealed a pelvic mass which proved to be a poorly differentiated serous carcinoma originating from the right residual tube which previously had not been removed during prophylactic surgery. This case report suggests that much effort should be made during prophylactic oophorectomy to completely remove the tubes, especially in light of the recent pathologic theories on the tubal origin of ovarian cancer.http://www.karger.com/Article/FullText/346339Ovarian cancerFallopian tubeBRCA mutationKurman’s hypothesis
collection DOAJ
language English
format Article
sources DOAJ
author Domenica Lorusso
Roberta Di Rocco
Maria Mancini
Francesco Raspagliesi
spellingShingle Domenica Lorusso
Roberta Di Rocco
Maria Mancini
Francesco Raspagliesi
High-Grade Serous Tumor Arising from Fallopian Tube in a BRCA Mutation Carrier after Prophylactic Oophorectomy
Case Reports in Oncology
Ovarian cancer
Fallopian tube
BRCA mutation
Kurman’s hypothesis
author_facet Domenica Lorusso
Roberta Di Rocco
Maria Mancini
Francesco Raspagliesi
author_sort Domenica Lorusso
title High-Grade Serous Tumor Arising from Fallopian Tube in a BRCA Mutation Carrier after Prophylactic Oophorectomy
title_short High-Grade Serous Tumor Arising from Fallopian Tube in a BRCA Mutation Carrier after Prophylactic Oophorectomy
title_full High-Grade Serous Tumor Arising from Fallopian Tube in a BRCA Mutation Carrier after Prophylactic Oophorectomy
title_fullStr High-Grade Serous Tumor Arising from Fallopian Tube in a BRCA Mutation Carrier after Prophylactic Oophorectomy
title_full_unstemmed High-Grade Serous Tumor Arising from Fallopian Tube in a BRCA Mutation Carrier after Prophylactic Oophorectomy
title_sort high-grade serous tumor arising from fallopian tube in a brca mutation carrier after prophylactic oophorectomy
publisher Karger Publishers
series Case Reports in Oncology
issn 1662-6575
publishDate 2013-01-01
description We present the case of a 67-year-old patient with a BRCA1 mutation and breast cancer who underwent prophylactic oophorectomy. After 6 years, an abdominal computed tomography revealed a pelvic mass which proved to be a poorly differentiated serous carcinoma originating from the right residual tube which previously had not been removed during prophylactic surgery. This case report suggests that much effort should be made during prophylactic oophorectomy to completely remove the tubes, especially in light of the recent pathologic theories on the tubal origin of ovarian cancer.
topic Ovarian cancer
Fallopian tube
BRCA mutation
Kurman’s hypothesis
url http://www.karger.com/Article/FullText/346339
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AT robertadirocco highgradeseroustumorarisingfromfallopiantubeinabrcamutationcarrierafterprophylacticoophorectomy
AT mariamancini highgradeseroustumorarisingfromfallopiantubeinabrcamutationcarrierafterprophylacticoophorectomy
AT francescoraspagliesi highgradeseroustumorarisingfromfallopiantubeinabrcamutationcarrierafterprophylacticoophorectomy
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