Amorphous solid dispersion formation via solvent granulation – A case study with ritonavir and lopinavir
Herein, we evaluate the potential of using a simple solvent granulation process to prepare a binary drug amorphous solid dispersion (ASD) containing two anti-HIV drugs, ritonavir and lopinavir. The drugs were granulated onto a mixture of lactose and microcrystalline cellulose, followed by drying to...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2019-12-01
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| Series: | International Journal of Pharmaceutics: X |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590156719300490 |